PREPARATION AND EVALUATION OF COPROCESSED SUPERDISINTEGRANT IN THE DESIGN OF PROCHLORPERAZINE MALEATE FAST DISSOLVING TABLETS
نویسندگان
چکیده
منابع مشابه
Formulation Design of Novel Fast Disintegrating Tablets of Prochlorperazine Maleate
In the present work, fast disintegrating tablets of prochlorperazine maleate were prepared with a view to enhance patient compliance by direct compression method. Three superdisintegrants i.e., crospovidone, croscarmellose sodium and sodium starch glycolate in different ratios with MCC (Avicel, PH-102) along with directly compressible mannitol (Pearlitol SD 200) to enhance mouth feel. The prepa...
متن کاملStudies on jackfruit seed starch as a novel natural superdisintegrant for the design and evaluation of irbesartan fast dissolving tablets
BACKGROUND In the present investigation, an attempt was made to isolate starch from jackfruit seed powder and utilize it as a superdisintegrant to design fast dissolving tablets of irbesartan. METHODS Starch was isolated from jackfruit seeds via aqueous and alkali extraction processes and evaluated for its physicochemical properties, for phytochemical tests, and for acute toxicity studies. Ir...
متن کاملFast Dissolving Tablets: Preparation, Characterization and Evaluation: an Overview
Oral route is the most preferred route for administration of various drugs because it is regarded as safest, most convenient and economical route. Recently researcher developed the fast dissolving tablet (FDT) with improved patient compliance and convenience. FDTs are solid dosage forms which dissolve rapidly in saliva without chewing and additional water. FDTs overcome the disadvantages of con...
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In the present work, fast dissolving tablets of clonazepam were prepared by direct compression method with a view to enhance patient compliance. Three super-disintegrants, viz., crospovidone, croscarmellose sodium and sodium starch glycolate in different ratios with microcrystalline cellulose (Avicel PH-102) along with directly compressible mannitol (Pearlitol SD 200) to enhance mouth feel. The...
متن کاملDesign of Fast Disintegrating Tablets of Prochlorperazine Maleate by Effervescence Method
In the present work, fast disintegrating tablets of prochlorperazine maleate were designed with a view to enhance patient compliance by effervescent method. In this method, mixtures of sodium bicarbonate and anhydrous citric acid in different ratios along with crospovidone (2-10% w/w), croscarmellose sodium (2-10% w/w) were used as superdisintegrants. Estimation of prochlorperazine maleate in t...
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ژورنال
عنوان ژورنال: Journal of Drug Delivery and Therapeutics
سال: 2011
ISSN: 2250-1177
DOI: 10.22270/jddt.v1i2.35